Rozwój genetyki i nauk żywieniowych a działania na rzecz zachowania zdrowia

Grażyna  Nowicka

doi:10.21697/seb.2005.3.1.03

Opublikowane: 2005-12-31

Tom 3 Nr 1 (2005)

Rozwój genetyki i nauk żywieniowych a działania na rzecz zachowania zdrowia

Grażyna Nowicka

Studia Ecologiae et Bioethicae

Dział: Artykuły naukowe

https://doi.org/10.21697/seb.2005.3.1.03

Abstrakt

Nutrition is a factor of major importance for health and also for development of diet related disorders. Nowadays there is no doubts that interaction between genes and nutrition plays a key role in health risk prediction and disease prevention. Individual nutritional status is determined not only by food availability but also by genes that control food intake, nutrient absorption and metabolism. On the other hand nutrients can significantly influence different genes expression and metabolic processes. Knowledge of genetic susceptibility to disease will help identify people at enhance risk and their response to diet. The prevalence of the types of genes of interest may differ between populations. The same genotype does not confer the same risk in all populations because of differences in environmental factors and nutritional habits. Therefore, populations should not simply copy each other’s dietary recommendations. Based on genetic and nutritional studies the best way for expression of healthier phenotypes should be found and used to promote health and prevent different diseases development.

Słowa kluczowe:

genetyka, żywienie, metabolizm

Pobierz pliki

pdf

Zasady cytowania

Nowicka, G. . (2005). Rozwój genetyki i nauk żywieniowych a działania na rzecz zachowania zdrowia. Studia Ecologiae Et Bioethicae, 3(1), 83–90. https://doi.org/10.21697/seb.2005.3.1.03

Cited by / Share

Bibliografia

Anderle P., Farmer P., Berger A., Roberts M.A. Nutrigenomic approach to understand the mechanisms by which dietary long chain fatty acids induce gene signals and control mechanisms involved in carcinogenesis. Nutrition 2004, 20:103-8. DOI: https://doi.org/10.1016/j.nut.2003.09.018
Google Scholar

Blount B.C., Mack M.M., Wehr C.M. et al. Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: implications for cancer and neural damage. Proc. Natl. Acad. Sci. USA 1997, 94:3290-5. DOI: https://doi.org/10.1073/pnas.94.7.3290
Google Scholar

Caggiula A.W., Mustad V.A. Effects of dietary fat and fatty acids on coronary artery disease risk and total and lipoprotein cholesterol concentrations: epidemiologic studies. Am.J.Clin.Nutr. 1997, 65 (suppl):1597-1601. DOI: https://doi.org/10.1093/ajcn/65.5.1597S
Google Scholar

Claycombe U.J., Meydani S.N. Vitamin E and genomic. Mutation Res. 2001, 475: 37-44. DOI: https://doi.org/10.1016/S0027-5107(01)00077-X
Google Scholar

Cravo M., Fidalgo P., Pereira A.D. DNA methylation as an intermediate biomarker in colorectal cancer: modulation by folic acid supplementation. Eur. J. Cancer. Prev. 1994, 3:473-9. DOI: https://doi.org/10.1097/00008469-199411000-00004
Google Scholar

Dewailly E., Blanchet C., Lemieux S., Sauve L., Gingras S., Ayotte P., Holub B. N-3 fatty acids and cardiovascular disease risk factors among the Inuit of Nunarik. Am.J.Clin.Nutr. 2001, 74:464-73. DOI: https://doi.org/10.1093/ajcn/74.4.464
Google Scholar

Fenech M. Genomic Stability: A New Paradige for Recommended dietary Allowances (RDAs). In „Modern Aspects of Nutrition. Present Knowledge and Future Perspectives”, eds: Elmodfo L., Anklam E., Konig J.S.; Forum Nutr. Basel, Karger 2003, vol. 56, pp. 97-100.
Google Scholar

Fenech M., Aitken C., Rindalai J. Folate, vit. B12, homocysteine status and DNA damage in young australien adults. Carcinogenesis 1998, 19:1163-71. DOI: https://doi.org/10.1093/carcin/19.7.1163
Google Scholar

Fenech M., Ferguson L.R. (eds): Micronutrients and Genomic Stability. Mutation Res. 2001, Special Issue vol. 475. DOI: https://doi.org/10.1016/S0027-5107(01)00069-0
Google Scholar

Guttmacher A.E., Collins F.S. Genomic Medicine – A Primer. New. Engl. J.Med. 2002, 347: 1512-6. DOI: https://doi.org/10.1056/NEJMra012240
Google Scholar

Halliwell B. Vitamin C and genomic stability. Mutation Res. 2001; 475: 29-35 DOI: https://doi.org/10.1016/S0027-5107(01)00072-0
Google Scholar

Heinonen O.P., Huttunen J.K., albanes D. et al. The effect of vitamin E and beta-carotene on the incidence of lung cancer and other cancers in male smokers. New Engl. J. Med. 1994, 330:1029. DOI: https://doi.org/10.1056/NEJM199404143301501
Google Scholar

Hennekes C.H., Buring J.E., Manson J.E. et al. Lack of effect of long term supplementation with beta carotene on the incidence of malignant neoplasms and cardiovascular disease. New Engl. J. Med. 1996, 334:1145. DOI: https://doi.org/10.1056/NEJM199605023341801
Google Scholar

Kris-Etherton P., Harris W., Appel L., for the AHA Nutrition Committee. Omega-3 fatty acids and cardiovascular disease. New recommendations from the American Heart Association. Atheroscler.Thromb.Vasc.Biol. 2003, 23:151-2. DOI: https://doi.org/10.1161/01.ATV.0000057393.97337.AE
Google Scholar

Mc Caddon A., Hudson P., Abrahamsson L. et al. Analogues, aging and aberrat assimilation of vit. B12 in Alzheimer disease. Dementia Ger Cognitive Dis 2001, 12:133-7. DOI: https://doi.org/10.1159/000051247
Google Scholar

Milner J.A. Incorporating basic nutrition science into health interventtions for cancer prevention. J. Nutr. 2003, 133:3820S-26S. DOI: https://doi.org/10.1093/jn/133.11.3820S
Google Scholar

MRC Vitamin Study Research Group. Prevention of neutral tube defects: results of the Medical Research Council Vitamin Study. Lancet 1991, 338-131. DOI: https://doi.org/10.1016/0140-6736(91)90133-A
Google Scholar

Noir S., Leitch W., Falconer J., Garg M. Prevention of cardiac arrhythmia by dietary (n-3) polyunsaturated fatty acids and their mechanism of action. J.Nutr. 1997,127:383-93. DOI: https://doi.org/10.1093/jn/127.3.383
Google Scholar

Nowicka G. Układ genów a odpowiedź metaboliczna na zmiany składu diety. Żyw. Człow. Metab. 2000, 27:277-286.
Google Scholar

Price P.T., Nelson C.M., Clarke S.D. Omega-3 polyunsaturated fatty acids regulation of gene expression. Cur.Opin.Lipidol. 2000, 11:3-7. DOI: https://doi.org/10.1097/00041433-200002000-00002
Google Scholar

Pryor W.A., Stahl W., Cheryl L.R. Beta-Carotene: from biochemistry to clinical trials. Nutr. Rev. 2000, 58: 39-56. DOI: https://doi.org/10.1111/j.1753-4887.2000.tb07810.x
Google Scholar

Report of the Joint WHO/FAO expert consultation on Diet, Nutrition and the Prevention of Chronic Diseases. Geneva, Switzerland, 2002.
Google Scholar

Simopoulos A.P. Evolutionary Aspects of Nutrition and Health. Diet, Exercise, Genetic and Chronic Disease. World Rev. Nutr. Diet. Basel, Karger, 1999, vol. 84. DOI: https://doi.org/10.1159/isbn.978-3-318-00396-3
Google Scholar

Simopoulos A.P. Genetics. Implications for Nutrition. In „Modern Aspects of Nutrition, Present Knowledge and Future Perspectives”, Eds: Elmodfo L., Anklam E., Konig J.S. Forum Nutr. Basel, Karger 2003, vol. 56, pp. 226-9.
Google Scholar

Simopoulos A.P., Childs B. (eds). Genetic Variation and Nutrition. World Rev. Nutr. Diet. Basel, Karger, 1990, vol. 63.
Google Scholar

Simopoulos A.P., Nestel P.J. (eds). Genetic Variation and Dietary Response. World Rev. Nutr. Diet. Basel, Karger, 1997, vol. 80. DOI: https://doi.org/10.1159/isbn.978-3-318-00213-3
Google Scholar

Titenko-Holland N., Jacob R.A., Shang N. et al. Micronuclei in lymphocytes and exfoliated buccal cells of postmenopausal women with dietary changes in folate. Mutation Res. 1998, 417:101-14. DOI: https://doi.org/10.1016/S1383-5718(98)00104-1
Google Scholar

Trippi F., Botto N., Scarpo R. et al. Spontaneous and induced chromosome damage in somatic cells of sporadic and familial Alzheimer disease patients. Mutagenesis 2001, 16:323-7. DOI: https://doi.org/10.1093/mutage/16.4.323
Google Scholar

World Health Organization, Executive Board 113th Session: Integrated prevention of noncommunicable diseases. Draft global strategy on diet, physical activity and health. EB 113/44 Add. 1, 27 November 2003.
Google Scholar

Young V.R. A vision of the nutritional sciences in the third millenium. In „Modern Aspects of Nutrition. Present Knowledge and Future Prospectives”. Eds: Elmedfo L., Anklam E., Konig J.S. Forum Nutr. Basel, Karger 2003, 56:24-9.
Google Scholar